Numerical Modeling for Direct Granulation of Agrochemical Suspension Using Fluidized Bed

Granulation Time in Fluidized Bed Granulators

Size enlargement of fine powders by wet granulation involves mixing of fine particles with a binder liquid to form larger wet granules and drying them by evaporation of the binder liquid to form larger dry granules. Identification of the time for completion of granulation process is critical as further mixing of dry granules is providing extra energy for their attrition. In a batch fluidized be...

Fluidized Bed Spray Granulation – From process understanding to modeling of nucleation and dust integration

Fluidized bed spray granulation is a process to obtain coarse-grained particles directly from suspensions, solutions or melts, ready for sale without any need for post-treatment. The process combines spray drying with granulation and classification, thus allowing the product particle size distribution to be adjusted according to customer demands. Well-known applications include pharmaceutical p...

Influence of binder droplet dimension on granulation rate during fluidized bed granulation.

Here, we statistically identified the critical factor of the granulation rate during the fluidized bed granulation process. Lactose was selected as the excipient and was granulated with several binders, including hydroxypropyl cellulose, hydroxypropyl methyl cellulose, and polyvinylpyrrolidone. The viscosity, density, and surface tension of the binder solution, contact angle, and the work done ...

Improving Three Phase Modeling of Fluidized Bed Dryer

Heat transfer phenomena in batch fluidized bed dryer have been studied and analyzed using three phase model including solid phase, interstitial gas phase and bubble phase based on Rizzi model. New correlations of heat transfer coefficient to surrounding and convection heat transfer coefficient between solid and interstitial gas are being proposed. In addition, some modifications have been d...

Unsteady-State Modeling of the Fluidized Bed Polyethylene Reactor